A clinical study published in Arthroscopy: The Journal of Arthroscopic and Related Surgery suggests how Puregraft fat grafting could significantly improve knee functional status and symptom relief at 3 and 6 months, in patients with knee osteoarthritis.
Puregraft (PG) LLC is a wholly owned subsidiary of Bimini Health Tech.
In the independent double-blind randomized study, investigators randomized 30 patients into three groups: PG fat mixed with saline; PG fat mixed with low dose (1 Billion platelets) platelet rich plasma (PRP); and PG fat mixed with high dose (3 Billion platelets) PRP. Patients underwent a single intraarticular injection and were evaluated at 3 and 6 months. The authors reported that all treatments groups were effective in improving knee functional status and reducing symptoms, with a significant decrease observed at 6 months on all scores (except for low dose PRP using a standard index of knee function and for high dose PRP using a standard index of knee stiffness).
The majority of the patients with initial abnormal flexion or extension of the knee improved at 3 months (no difference between groups) and this global improvement was observed at 6 months. There were no study treatment-related adverse events, a media release from Bimini Health Tech explains.
“The investigators’ work lends further support to the emerging role of purified adipose in the treatment of osteoarthritic conditions.” Added Dr. Daniels, “Significant clinical improvement, with and without PRP, is a key patient and physician goal in this difficult to treat condition.”
— Dr. Eric Daniels, Chief Medical Officer of Puregraft
[Source(s): Bimini Health Tech, PR Newswire]
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