By acting to protect the collateral circulation that occurs in the brain, aerobic exercise may help lessen the severity of strokes later in life, according to the American Heart Association.
A study presented during the American Heart Association’s International Stroke Conference 2017 notes that as the brain ages, the number of blood vessels shrinks in number and diameter. Collateral circulation allows blood flow to be rerouted when arteries narrow.
The amount of damage to the brain after a stroke and the effectiveness of recovery treatments depend significantly on the extent of collateral circulation, explains a media release from the American Heart Association.
In the study using mice, researchers suggest that exercise prevents this loss of collateral vessels.
Mice that started exercising regularly at 12 months-age (equivalent to 40 years-age in humans) had the same abundance of collateral vessels when they reached 25 months-age (equivalent to 70 humans years) as seen at 3 months-age (equivalent to 16 human years), unlike their non-exercising 25-month-old counterparts who had fewer collaterals of smaller diameter, per the release.
When the exercising 25-month-old mice suffered strokes, they had much less brain damage—ie, the same as seen in young 3-month-old mice. The exercising mice also had higher levels of molecules that help blood vessels work properly and stay healthy, the release continues.
The researchers conclude in the release that, according to their findings, regular aerobic exercise may protect the collateral circulation and lessen the severity of strokes later in life.
[Source(s): American Heart Association, Science Daily]