Physical therapy can be a useful, nonpharmacologic approach for managing severe musculoskeletal pain, suggest researchers from Stanford University School of Medicine and the Duke University School of Medicine, in a study published in JAMA Network Open.

Patients who underwent physical therapy soon after being diagnosed with pain in the shoulder, neck, low back, or knee were approximately 7% to 16% less likely to use opioids in the subsequent months.

In addition, for patients with shoulder, back or knee pain who did use opioids, early physical therapy was associated with a 5% to 10% reduction in how much of the drug they used, the researchers suggest, in a media release from Stanford Medicine.

“We asked ourselves, ‘How can we address the pain that people are having, while not increasing their risk of needing opioids?'” says Eric Sun, MD, PhD, assistant professor of anesthesiology, perioperative, and pain medicine at Stanford. “And what our study found was that if you can get these patients on physical therapy reasonably quickly, that reduces the probability that they’ll be using opioids in the longer term.”

In the study, Sun and senior author Steven George, PhD, professor of orthopaedic surgery at Duke, analyzed private health insurance claims for care and prescriptions between 2007 and 2015. They also reviewed claims for outpatient and emergency room visits for the earliest instance of a diagnosis of shoulder, neck, knee, or low back pain among privately insured, nonelderly adult patients.

The study screened out patients who had recently taken opioids by including only those who hadn’t filled an opioid prescription within the prior year. The study also screened out patients with less serious pain by including only those who had visited a doctor for their condition within 30 days of their initial diagnosis and were given at least one opioid prescription within 90 days. The final sample consisted of 88,985 patients, the release explains.

After adjusting for co-morbidities, such as diabetes and hypertension, Sun and his colleagues found that the odds of patients filling an opioid prescription 3 months to a year after their initial pain diagnosis were lower if they had participated in at least one physical therapy session within 90 days of their diagnosis. The odds were reduced by 16% for patients with knee pain, 15% for shoulder pain, 8% for neck pain, and 7% for lower back pain.

The findings, Sun states, could be helpful to clinicians in search of pain-management options that carry fewer health risks than opioids. Studies have shown that exercise therapy, a component of physical therapy, reduces pain and improves function for some musculoskeletal conditions. Other studies have shown that patients with past prescriptions for opioid pain medication are at increased risk for overdose and misuse.

“This isn’t a world where there are magic bullets,” Sun adds. “But many guidelines suggest that physical therapy is an important component of pain management, and there is little downside to trying it.”

The study also measured whether early physical therapy was associated with a decreased need for opioids in the long term among patients who filled prescriptions. The researchers measured the quantity of opioids by converting prescribed amounts to oral morphine milligram equivalents.

They found, after adjusting for confounding factors, that patients who had undergone early physical therapy used 10.3% less opioid medication for knee pain; 9.7% less for shoulder pain; and 5.1% less for back pain in the period 3 months to a year after their diagnosis. There was no significant reduction for neck pain.

Physical therapy within 3 months of diagnosis also was associated with a decreased likelihood that patients with two of the conditions would chronically use opioids in the long term, according to the study. After early physical therapy, patients with knee pain were 66% less likely in the period 3 months to a year after their diagnosis to either fill 10 or more prescriptions or acquire a supply of opioid medication for 120 days or more. Patients with low back pain were 34% less likely to be chronic users if they had early physical therapy. There was no association between physical therapy and chronic opioid use among patients with shoulder or neck pain.

“The general consensus is that for musculoskeletal pain, opioids generally aren’t a long-term solution,” Sun concludes. “Aside from all the other side effects, even if the medication is doing well for you, it will have less and less effect over time as your body builds up a tolerance.”

[Source(s0): Stanford Medicine, EurekAlert]