Repetitive heading of the soccer ball results in more extensive changes to the brain tissue in women soccer players than in men, suggests a study published recently in the journal Radiology.
“In general, men do a lot more heading than women, but we wanted to specifically examine if men and women fare similarly or differently with a similar amount of exposure to repeated impacts to the head,” says the study’s lead author, Michael L. Lipton, MD, PhD, in a media release from the Radiological Society of North America.
Lipton is a professor of radiology at the Gruss Magnetic Resonance Research Center at the Albert Einstein College of Medicine and medical director of MRI at Montefiore Medical Center in New York City, per the release.
In the study, Lipton and colleagues used diffusion tensor imaging (DTI), an advanced MRI technique, to assess microscopic changes in the brain’s white matter in 98 amateur soccer players—49 men and 49 women—with an average age of 25.8 years. All participants had many years of soccer and heading exposure, including 12 months of frequent heading exposure leading up to the study (median headers: 487 per year for the men and 469 per year for the women). Participants had no significant differences in demographic factors.
DTI produces a measurement, called fractional anisotropy (FA), which characterizes the movement of water molecules in the brain. In healthy white matter, the direction of water movement is fairly uniform and measures high in FA. When water movement is more random, FA values decrease.
“A decline in FA is an indicator of changes in the white matter microstructure that may be indicative of inflammation or loss of neurons, for example,” Lipton says.
After comparing white matter FA values among the male and female soccer players, the researchers found that while both men and women experienced lower FA values related to more repetitive heading, women exhibited lower FA levels across a much larger volume of brain tissue.
“In both groups, this effect we see in the brain’s white matter increased with greater amounts of heading,” Lipton adds. “But women exhibit about five times as much microstructural abnormality as men when they have similar amounts of heading exposure.”
Researchers were also able to identify specific regions of the brain where frequent heading was associated with lower FA: three brain regions in men and eight brain regions in women.
“The important message from these findings is that there are individuals who are going to be more sensitive to heading than others,” Lipton shares. “Our study provides preliminary support that women are more sensitive to these types of head impacts at the level of brain tissue microstructure.”
He cautions, however, that more investigation is warranted to confirm and further characterize gender differences in vulnerability to brain injury due to heading.
“We don’t have enough information yet to establish guidelines to protect the players,” Lipton says. “But by understanding these relationships—how different people have different levels of sensitivity to heading—we can get to the point of determining the need for gender-specific recommendations for safer soccer play.”
[Source(s): Radiological Society of North America, EurekAlert]
